In the News
Articles represent the views of their authors and not necessarily those of ME/CFS Australia. Some links lead to articles on third party websites.
New Poetry Collection Explores Living With Chronic Illness
A new poetry collection, written by a York man, is shining a light on life with chronic illness. Written by 68-year-old Bill Clayton from Fulford, The Word Doodle Trilogy explores his experience of living with ME/CFS, alongside reflections on military service and everyday moments.
Endoplasmic Reticulum Stress And Oxidative Imbalance Is The Missing Link In Fibromyalgia Pathophysiology
This study aimed to investigate the involvement of endoplasmic reticulum (ER) stress in Fibromyalgia syndrome (FMS) by evaluating key ER stress markers and oxidative stress parameters in patients with FMS.
Low-Dose Rapamycin Alleviates Clinical Symptoms Of Fatigue And PEM In ME/CFS Patients Via Improvement Of Autophagy: A Pilot Study
mTOR activation is associated with chronic inflammation in ME/CFS. Previous studies have shown that sustained mTOR activation may cause chronic muscle fatigue by inhibiting ATG13-mediated autophagy. However, the therapeutic implication of this finding has not been established. Given that rapamycin is an mTOR inhibitor, this study aims to investigate whether low-dose rapamycin treatment improves autophagy markers and clinical symptoms of fatigue in ME/CFS subjects. This highlights the pivotal role of mTOR in the pathogenesis of ME/CFS.
Nuclear Magnetic Resonance-Based Metabolomic Profiling In Fibromyalgia Patients
This study compared the metabolic profiles of Fibromyalgia patients and healthy controls using one-dimensional (1D) 1H nuclear magnetic resonance (NMR) spectroscopy and multivariate statistical analysis to identify potential biomarkers associated with Fibromyalgia symptoms.
Placebo Outperforms CBD For FM Pain
New Danish research published in Annals of the Rheumatic Diseases suggest cannabidiol does not provide pain relief in fibromyalgia patients.
ME/CFS As A Sickness Behaviour-Like Response To HSV-1 Infection Within The Brain: A Hypothesis
This work presents the hypothesis that a Herpes Simplex Virus 1 (HSV-1) infection in the brain is a significant contributor to the symptoms experienced by a subset of ME/CFS patients.
The Microbiota-Gut-Brain Axis In Mental And Neurodegenerative Disorders: Opportunities For Prevention And Intervention
This review synthesizes current evidence linking microbiota alterations to diseases including Chronic Fatigue Syndrome.
Physical Capacity Modulates Intestinal Barrier Dysfunction In Functional Disorders: Phenotype-Specific Patterns In Fibromyalgia And Irritable Bowel Syndrome
Research published in Frontiers in Physiology.
Atopic Dermatitis Significantly Raises Risk Of Fibromyalgia, New Study Shows
Patients with atopic dermatitis (AD) face a markedly higher likelihood of developing fibromyalgia, a large Taiwanese cohort study published in the Indian Journal of Dermatology, Venereology and Leprology has suggested.
Myalgic Encephalomyelitis: Beyond Effort And Deconditioning
In a compelling and much-needed scientific dialogue, a fresh reply has emerged in the ongoing debate surrounding the elusive and debilitating condition known as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The reply, authored by Walitt, Chin, Drinkard, and colleagues, responds directly to claims that dismiss altered effort and deconditioning as invalid explanations for ME/CFS. Published in Nature Communications, this discourse delves deep into the neurobiological and physiological underpinnings of the syndrome, challenging misconceptions that have long clouded both clinical understanding and patient care.
Altered Effort And Deconditioning Are Not Valid Explanations Of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Research published in Nature Communications.
The Genetic Association Between Prescription Pain Medication Use And The Risk For Fibromyalgia: A Bidirectional And Multivariable Mendelian Randomization Analysis
Increasing evidence has indicated that prescription opioid use is associated with poor prognosis in patients with fibromyalgia. However, it remains unknown whether there are causal associations between prescription opioid and fibromyalgia.